Across TCGA patient cohorts, IL3RA protein abundance is significantly associated with the RNA expression of many other genes, with 7,347 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL3RA-associated genes across cancer lineages are CNNM4, PLCB1, and ATRN. Each is linked with IL3RA in more than 2 cancer types. Because this analysis shows association rather than direction, both IL3RA-to-partner and partner-to-IL3RA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL3RA→partner) and Y-score (partner→IL3RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CNNM4 →	-0.742	-0.763	<.001	.008	3	3
HNSC	PLCB1 →	-1.440	-0.958	.006	<.001	3	3
HNSC	ATRN →	-1.147	-0.828	.001	.003	3	3
HNSC	COTL1 →	+1.604	+1.267	.003	.005	3	3
HNSC	ZBP1 →	+2.142	+1.195	.002	<.001	3	3
HNSC	CD7 →	+1.865	+1.344	.006	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,347 associations by consensus.

Exploration

IL3RA survival (RNA) · tumor vs normal (RNA) · all IL3RA data types