Across TCGA patient cohorts, IL3RA mutation is significantly associated with the RNA expression of many other genes, with 2,814 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL3RA-associated genes across cancer lineages are PLBD2, KLF13, and ALG12. Each is linked with IL3RA in more than 2 cancer types. Because this analysis shows association rather than direction, both IL3RA-to-partner and partner-to-IL3RA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL3RA→partner) and Y-score (partner→IL3RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PLBD2 →	+0.349	+1.545	.004	.005	3	3
UCEC	KLF13 →	+0.528	+2.593	.002	<.001	3	3
UCEC	ALG12 →	+0.591	+1.809	.001	.001	3	3
UCEC	TANGO2 →	+0.477	+2.069	<.001	<.001	3	3
UCEC	RHBDD3 →	+0.412	+3.000	.001	<.001	3	3
BLCA	LINC02644 →	+0.072	+4.033	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,814 associations by consensus.

Exploration

IL3RA survival (RNA) · tumor vs normal (RNA) · all IL3RA data types