IL37

Across TCGA patient cohorts, IL37 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,066 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IL37-associated proteins across cancer lineages are KPNA2, MKI67_S2828, and PRC1. Each is linked with IL37 in more than 3 cancer types. Because this analysis shows association rather than direction, both IL37-to-partner and partner-to-IL37 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL37 versus KPNA2 in GBM, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL37→partner) and Y-score (partner→IL37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KPNA2 →	+0.630	+0.573	<.001	<.001	3	4
BRCA	MKI67_S2828 →	+0.779	+0.402	.002	.001	3	4
BRCA	PRC1 →	+0.627	+0.461	<.001	<.001	3	3
GBM	WDHD1 →	+0.629	+0.508	<.001	<.001	3	3
LUAD	PLXDC2_S495 →	-1.028	-2.018	<.001	.005	3	3
UCEC	SLC41A3 →	-0.465	-0.789	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,066 associations by consensus.

IL37 vs KPNA2 — GBM

Explore this scatter interactively →