IL37

Across TCGA patient cohorts, IL37 protein abundance is significantly associated with the RNA expression of many other genes, with 1,550 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IL37-associated genes across cancer lineages are JOSD1, MTMR3, and NOL4. Each is linked with IL37 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL37-to-partner and partner-to-IL37 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL37 versus JOSD1 in LUAD, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL37→partner) and Y-score (partner→IL37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	JOSD1 →	+0.405	+1.157	<.001	.004	3	1
LUAD	MTMR3 →	+0.398	+1.353	.009	.008	3	1
LUAD	NOL4 →	-0.367	-1.428	.009	.001	3	1
LUAD	VSIG1 →	+2.501	+1.603	<.001	.004	3	1
LUAD	ATG4A →	+0.512	+1.631	.007	.002	3	1
LUAD	STS →	+0.626	+1.311	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,550 associations by consensus.

IL37 vs JOSD1 — LUAD

Explore this scatter interactively →