IL37

Across TCGA cell cohorts, IL37 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,391 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IL37-associated GO terms across cancer lineages are Transposable element silencing by piRNA-mediated heterochromatin formation, Regulation of sodium ion export across plasma membrane, and Positive regulation of sodium ion export across plasma membrane. Each is linked with IL37 in more than 8 cancer types. Because this analysis shows association rather than direction, both IL37-to-partner and partner-to-IL37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transposable element silencing by piRNA-mediated heterochromatin formation grouped by IL37-low versus IL37-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL37→partner) and Y-score (partner→IL37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transposable element silencing by piRNA-mediated heterochromatin formation →	+1.439	+0.178	<.001	.003	3	8
BONE	Regulation of sodium ion export across plasma membrane →	+0.241	+0.178	.005	.004	3	8
BONE	Positive regulation of sodium ion export across plasma membrane →	+0.241	+0.178	.005	.004	3	8
PANCREAS	Positive regulation of chemotaxis →	+0.104	+1.038	<.001	<.001	2	9
LUNG_SCLC	Zinc ion import across plasma membrane →	-0.098	-0.250	<.001	.002	3	7
BONE	Negative regulation of small GTPase mediated signal transduction →	+0.086	+0.198	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,391 associations by consensus.

Transposable element silencing by piRNA-mediated heterochromatin formation by IL37 expression — BONE

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