IL34

Across TCGA patient cohorts, IL34 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,731 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IL34-associated proteins across cancer lineages are ADD3, CELF2, and CLIC2. Each is linked with IL34 in more than 5 cancer types. Because this analysis shows association rather than direction, both IL34-to-partner and partner-to-IL34 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL34 versus ADD3 in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL34→partner) and Y-score (partner→IL34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ADD3 →	+0.302	+1.033	.001	<.001	3	6
BRCA	CELF2 →	+0.585	+1.132	<.001	.002	3	6
UCEC	CLIC2 →	+0.499	+0.713	<.001	<.001	3	6
CCRCC	FBLN5 →	+0.934	+0.644	<.001	.001	3	6
BRCA	NAA35 →	-0.199	-0.963	<.001	<.001	3	6
PDAC	PLAC9 →	+0.824	+0.722	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,731 associations by consensus.

IL34 vs ADD3 — HNSC

Explore this scatter interactively →