IL34

Across TCGA cell cohorts, IL34 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,636 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible IL34-associated GO terms across cancer lineages are Response to topologically incorrect protein, Golgi vesicle transport, and Negative regulation of cell adhesion. Each is linked with IL34 in more than 10 cancer types. Because this analysis shows association rather than direction, both IL34-to-partner and partner-to-IL34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to topologically incorrect protein grouped by IL34-low versus IL34-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL34→partner) and Y-score (partner→IL34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Response to topologically incorrect protein →	+0.092	+0.654	.001	.001	3	11
STOMACH	Golgi vesicle transport →	+0.059	+0.508	<.001	<.001	3	10
BREAST	Negative regulation of cell adhesion →	+0.075	+0.745	<.001	<.001	3	9
STOMACH	Viral life cycle →	+0.094	+0.714	<.001	<.001	3	9
OESOPHAGUS	Nuclear receptor-mediated signaling pathway →	+0.078	+0.272	<.001	.004	3	9
SOFT_TISSUE	Response to oxygen levels →	+0.058	+1.086	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,636 associations by consensus.

Response to topologically incorrect protein by IL34 expression — STOMACH

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