IL31RA

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, IL31RA Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IL31RA data layer compared with 28 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher IL31RA Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated IL31RA expression acts as an unfavorable survival marker.

LGG, PRAD, and LIHC are the cancer types where IL31RA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LGGOSMedianAll0.3070.799.0126view →
PRADDFSMedianAll0.0850.774<.0016view →
LIHCOSMedianAll0.1640.707.0013view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

IL31RA–LGG (OS)

Kaplan–Meier survival curve for IL31RA mutant vs wild-type samples in LGG.

Open the LGG breakdown →

Exploration