Across TCGA patient cohorts, IL31 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,496 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IL31-associated GO terms across cancer lineages are Nuclear envelope organization, U2-type prespliceosome assembly, and Regulation of protein localization to chromosome, telomeric region. Each is linked with IL31 in more than 13 cancer types. Because this analysis shows association rather than direction, both IL31-to-partner and partner-to-IL31 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL31→partner) and Y-score (partner→IL31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nuclear envelope organization →	+0.079	+0.221	<.001	<.001	3	14
STAD	U2-type prespliceosome assembly →	+0.084	+0.190	<.001	<.001	3	14
STAD	Regulation of protein localization to chromosome, telomeric region →	+0.080	+0.188	<.001	<.001	3	13
STAD	Cellular respiration →	+0.074	+0.239	<.001	<.001	3	13
STAD	Aerobic respiration →	+0.077	+0.205	<.001	<.001	3	13
STAD	Positive regulation of cell cycle phase transition →	+0.061	+0.221	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,496 associations by consensus.

Exploration

IL31 survival (RNA) · tumor vs normal (RNA) · all IL31 data types