IL2RB

Across TCGA pan-cancer cohorts, IL2RB mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated IL2RB data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher IL2RB mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated IL2RB expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD and UCEC are the cancer types where IL2RB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.392	0.745	.040	13	view →
UCEC	DFS	Quartile	All	0.966	0.807	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

IL2RB–LUAD (DFS)

Open the LUAD breakdown →