IL2RB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IL2RB protein abundance is significantly associated with the RNA expression of many other genes, with 2,457 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL2RB-associated genes across cancer lineages are WNT6, PGBD1, and FXYD6. Each is linked with IL2RB in more than 1 cancer types. Because this analysis shows association rather than direction, both IL2RB-to-partner and partner-to-IL2RB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL2RB versus WNT6 in UCEC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL2RB→partner) and Y-score (partner→IL2RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECWNT6 →-1.101-0.607<.001<.00132
UCECPGBD1 →-0.645-0.803<.001<.00132
CCRCCFXYD6 →-0.906-0.917.006.00132
CCRCCFANCC →-0.665-0.990.001<.00132
UCECSV2A →-0.772-0.765.002<.00132
LUADPRKAR1B →-0.694-0.525<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,457 associations by consensus.

IL2RB vs WNT6 — UCEC

Per-sample scatter of IL2RB vs WNT6 in UCEC (Pearson r = -0.35).

Explore this scatter interactively →

Exploration