IL2RB

Across TCGA cell cohorts, IL2RB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,181 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IL2RB-associated GO terms across cancer lineages are Aerobic respiration, Membrane depolarization, and Monosaccharide metabolic process. Each is linked with IL2RB in more than 6 cancer types. Because this analysis shows association rather than direction, both IL2RB-to-partner and partner-to-IL2RB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by IL2RB-low versus IL2RB-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL2RB→partner) and Y-score (partner→IL2RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Aerobic respiration →	+0.070	+3.080	<.001	<.001	3	7
CNS	Membrane depolarization →	-0.044	-0.490	<.001	.008	3	6
BLOOD_Lymphoma	Monosaccharide metabolic process →	+0.040	+2.597	<.001	<.001	3	6
LARGE_INTESTINE	Regulation of protein deubiquitination →	+0.098	+0.085	.001	.002	3	6
UPPER_AERODIGESTIVE_TRACT	Response to starvation →	+0.042	+0.242	.001	.004	2	7
PANCREAS	Plasma membrane raft assembly →	+0.149	+0.143	.006	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,181 associations by consensus.

Aerobic respiration by IL2RB expression — BLOOD_Lymphoma

Explore this box plot interactively →