IL2RA

Across TCGA patient cohorts, IL2RA RNA expression is significantly associated with the protein abundance of many other proteins, with 23,702 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL2RA-associated proteins across cancer lineages are SAMSN1_S23, PTPN7, and PLEK. Each is linked with IL2RA in more than 9 cancer types. Because this analysis shows association rather than direction, both IL2RA-to-partner and partner-to-IL2RA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL2RA versus SAMSN1_S23 in BRCA, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL2RA→partner) and Y-score (partner→IL2RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SAMSN1_S23 →	+0.900	+0.974	<.001	<.001	3	10
OV	PTPN7 →	+0.763	+1.142	<.001	<.001	3	10
UCEC	PLEK →	+0.806	+0.897	<.001	<.001	3	10
GBM	CD163 →	+1.214	+1.702	<.001	<.001	3	10
GBM	DOK2 →	+0.845	+1.746	<.001	<.001	3	10
GBM	AIF1 →	+0.884	+1.554	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,702 associations by consensus.

IL2RA vs SAMSN1_S23 — BRCA

Explore this scatter interactively →