IL27RA

Across TCGA patient cohorts, IL27RA protein abundance is significantly associated with the RNA expression of many other genes, with 2,405 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IL27RA-associated genes across cancer lineages are LRRC4, RUNDC3A, and GBE1. Each is linked with IL27RA in more than 1 cancer types. Because this analysis shows association rather than direction, both IL27RA-to-partner and partner-to-IL27RA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL27RA versus LRRC4 in GBM, with a Pearson correlation of -0.91.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL27RA→partner) and Y-score (partner→IL27RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LRRC4 →	-1.886	-0.890	.001	.003	3	2
GBM	RUNDC3A →	-1.967	-0.735	.007	.002	3	2
GBM	GBE1 →	+1.460	+0.890	.008	.003	3	2
LUAD	MVP →	+0.712	+0.482	<.001	<.001	3	2
LUAD	NCKAP5-AS2 →	-0.758	-0.289	.005	.004	3	2
GBM	CLEC5A →	+2.136	+0.969	.006	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,405 associations by consensus.

IL27RA vs LRRC4 — GBM

Explore this scatter interactively →