IL27RA

Across TCGA cell cohorts, IL27RA RNA expression is significantly associated with the go_rna of many other GO terms, with 5,074 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IL27RA-associated GO terms across cancer lineages are Regulation of T cell extravasation, Negative regulation of T cell migration, and Purine nucleoside monophosphate biosynthetic process. Each is linked with IL27RA in more than 14 cancer types. Because this analysis shows association rather than direction, both IL27RA-to-partner and partner-to-IL27RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of T cell extravasation grouped by IL27RA-low versus IL27RA-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL27RA→partner) and Y-score (partner→IL27RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of T cell extravasation →	+0.626	+1.229	.008	.002	2	15
URINARY_TRACT	Negative regulation of T cell migration →	+1.512	+1.736	<.001	<.001	3	14
LARGE_INTESTINE	Purine nucleoside monophosphate biosynthetic process →	+0.109	+1.372	<.001	<.001	3	10
LARGE_INTESTINE	IMP biosynthetic process →	+0.147	+1.467	<.001	<.001	3	9
BLOOD_Lymphoma	Protein folding →	+0.048	+1.178	<.001	.002	3	9
LUNG_NSCLC_LUSC	Foam cell differentiation →	+0.270	+1.718	.003	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,074 associations by consensus.

Regulation of T cell extravasation by IL27RA expression — LUNG_SCLC

Explore this box plot interactively →