Across TCGA cell cohorts, IL27 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,001 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible IL27-associated GO terms across cancer lineages are Inner cell mass cell differentiation, Regulation of phagosome maturation, and Response to yeast. Each is linked with IL27 in more than 3 cancer types. Because this analysis shows association rather than direction, both IL27-to-partner and partner-to-IL27 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL27→partner) and Y-score (partner→IL27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Inner cell mass cell differentiation →	+1.169	+0.335	<.001	.001	3	4
BREAST	Regulation of phagosome maturation →	+0.542	+0.252	.001	.005	3	4
BREAST	Response to yeast →	-0.105	-0.188	.008	.003	3	3
BREAST	Positive regulation of relaxation of muscle →	-1.168	-0.226	<.001	<.001	3	3
BREAST	Ceramide 1-phosphate transport →	+0.117	+0.212	<.001	.008	3	3
BREAST	Positive regulation of miRNA processing →	-0.115	-0.290	.002	.008	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,001 associations by consensus.

Exploration

IL27 survival (RNA) · tumor vs normal (RNA) · all IL27 data types