IL24

Across TCGA patient cohorts, IL24 mutation is significantly associated with the RNA expression of many other genes, with 224 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL24-associated genes across cancer lineages are MIR193A, OR4F21, and HIGD1AP15. Each is linked with IL24 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL24-to-partner and partner-to-IL24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR193A grouped by IL24-low versus IL24-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL24→partner) and Y-score (partner→IL24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR193A →	+1.056	+3.785	<.001	.005	3	2
PRAD	OR4F21 →	+0.061	+5.420	<.001	.005	3	1
PRAD	HIGD1AP15 →	+0.140	+5.166	.005	.007	3	1
PRAD	MTND2P8 →	+0.052	+5.288	<.001	.006	3	1
HNSC	MIR378D1 →	+0.461	+7.954	<.001	.008	3	1
HNSC	MIR4490 →	+0.328	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 224 associations by consensus.

MIR193A by IL24 expression — COAD

Explore this box plot interactively →