IL24

Across TCGA pan-cancer cohorts, IL24 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated IL24 data layer compared with 2 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher IL24 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IL24 expression acts as an unfavorable survival marker, although some lineages such as BRCA and MESO show a favorable association.

UVM, BRCA, and MESO are the cancer types where IL24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.413	0.763	<.001	94	view →
BRCA	DFS	Tertile	All	0.967	0.931	<.001	81	view →
MESO	OS	Tertile	All	0.515	0.265	.001	56	view →
LUAD	DFS	Median	All	0.731	0.600	<.001	43	view →
KIRP	OS	Tertile	III,IV	0.289	0.690	.006	40	view →
LIHC	DFS	Tertile	All	0.663	0.503	.017	19	view →
SARC	OS	Tertile	All	0.852	0.625	<.001	18	view →
ESCA	DFS	Tertile	II,III,IV	0.564	0.289	.013	15	view →
CHOL	DFS	Tertile	All	0.617	0.146	.006	15	view →
LGG	OS	Median	All	0.452	0.600	.008	14	view →
THYM	OS	Median	All	1.000	0.654	.005	9	view →
BLCA	DFS	Median	III,IV	0.634	0.501	.017	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

IL24–UVM (OS)

Open the UVM breakdown →