IL23R

Across TCGA pan-cancer cohorts, IL23R mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated IL23R data layer compared with 19 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IL23R mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated IL23R expression acts as an unfavorable survival marker.

HNSC and PDAC are the cancer types where IL23R mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	III,IV	0.744	1.000	.008	15	view →
PDAC	OS	Quartile	All	0.450	0.806	.034	14	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

IL23R–HNSC (DFS)

Open the HNSC breakdown →