IL20RB

Across TCGA patient cohorts, IL20RB mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL20RB-associated genes across cancer lineages are Cyclin-B1, JNK2, and Ku80. Each is linked with IL20RB in more than 1 cancer types. Because this analysis shows association rather than direction, both IL20RB-to-partner and partner-to-IL20RB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by IL20RB-low versus IL20RB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL20RB→partner) and Y-score (partner→IL20RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.604	+2.321	.009	.006	3	2
UCEC	JNK2 →	+0.218	+3.348	.007	.004	3	1
UCEC	Ku80 →	+0.218	+1.884	.025	.030	3	1
UCEC	MEK1 →	+0.459	+3.700	.002	.001	3	1
UCEC	Notch1 →	+0.251	+3.920	<.001	<.001	3	1
UCEC	PDCD4 →	-0.599	-1.807	.002	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Cyclin-B1 by IL20RB expression — UCEC

Explore this box plot interactively →