IL20RB

Across TCGA pan-cancer cohorts, IL20RB RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of IL20RB’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where IL20RB RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IL20RB is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

KIRC, LUSC, and LUAD are the cancer types where IL20RB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IL20RB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+3.284	<.001	12	view →
LUSC	Male	All	+3.620	<.001	8	view →
LUAD	Female	II,III,IV	+1.981	<.001	8	view →
THCA	Male	II,III,IV	−0.410	<.001	8	view →
KIRP	All	All	+0.951	<.001	7	view →
BRCA	All	III,IV	−0.499	<.001	4	view →
UCEC	All	All	+0.431	.009	4	view →
BLCA	Male	III,IV	+1.825	.013	3	view →
READ	All	II,III,IV	+0.480	.003	3	view →
PAAD	All	All	+2.915	.010	2	view →
PRAD	All	All	−0.697	<.001	2	view →
KICH	Female	All	−0.244	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

IL20RB–KIRC

Open the KIRC breakdown →