IL20RB

Across TCGA cell cohorts, IL20RB mutation is significantly associated with the mutation status of many other genes, with 1,333 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL20RB-associated genes across cancer lineages are MAP2K4, GPR171, and ATG13. Each is linked with IL20RB in more than 2 cancer types. Because this analysis shows association rather than direction, both IL20RB-to-partner and partner-to-IL20RB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAP2K4 grouped by IL20RB-low versus IL20RB-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL20RB→partner) and Y-score (partner→IL20RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAP2K4 →	+2.865	+4.217	.007	.007	1	3
LARGE_INTESTINE	GPR171 →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	ATG13 →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	OR10P1 →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	B3GNT8 →	+5.672	+5.672	<.001	<.001	1	2
LARGE_INTESTINE	OR2T12 →	+5.087	+4.523	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,333 associations by consensus.

MAP2K4 by IL20RB expression — LARGE_INTESTINE

Explore this box plot interactively →