IL20RA

Across TCGA patient cohorts, IL20RA mutation is significantly associated with the RNA expression of many other genes, with 1,188 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL20RA-associated genes across cancer lineages are TEX50, RN7SKP282, and OR4N1P. Each is linked with IL20RA in more than 1 cancer types. Because this analysis shows association rather than direction, both IL20RA-to-partner and partner-to-IL20RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX50 grouped by IL20RA-low versus IL20RA-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL20RA→partner) and Y-score (partner→IL20RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TEX50 →	+0.111	+5.736	<.001	.003	3	2
HNSC	RN7SKP282 →	+0.209	+5.435	<.001	.005	3	2
HNSC	OR4N1P →	+0.068	+5.368	<.001	.005	3	2
HNSC	TEKT4P3 →	+0.722	+5.182	<.001	.007	3	2
UCEC	ACACA →	+0.640	+2.136	.001	.009	3	2
UCEC	MIR5696 →	+0.193	+2.901	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,188 associations by consensus.

TEX50 by IL20RA expression — HNSC

Explore this box plot interactively →