IL20RA

Across TCGA pan-cancer cohorts, IL20RA RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of IL20RA’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where IL20RA RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IL20RA is over-expressed in tumor, although a few such as KIRC and LUAD show the opposite, repressed pattern.

COAD, KIRC, and LUAD are the cancer types where IL20RA tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IL20RA RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+1.346	<.001	11	view →
KIRC	Female	All	−0.586	<.001	11	view →
LUAD	All	III,IV	−1.885	<.001	9	view →
THCA	Male	All	−1.355	<.001	9	view →
STAD	All	All	+0.760	.005	7	view →
BLCA	Male	All	+2.073	<.001	6	view →
UCEC	All	II,III,IV	−1.909	<.001	6	view →
BRCA	Female	All	−0.977	<.001	6	view →
CHOL	Male	All	+3.330	<.001	4	view →
LUSC	All	All	−0.559	.008	3	view →
READ	Female	All	+1.676	<.001	2	view →
HNSC	All	II,III,IV	−0.479	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

IL20RA–COAD

Open the COAD breakdown →