IL20RA

Across TCGA patient cohorts, IL20RA mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL20RA-associated genes across cancer lineages are Caspase-7-cleavedD198, ERK2, and MEK1. Each is linked with IL20RA in more than 1 cancer types. Because this analysis shows association rather than direction, both IL20RA-to-partner and partner-to-IL20RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by IL20RA-low versus IL20RA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL20RA→partner) and Y-score (partner→IL20RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.986	+3.906	<.001	<.001	3	2
UCEC	ERK2 →	+0.217	+2.115	.009	.019	3	1
UCEC	MEK1 →	+0.334	+3.169	.036	.019	3	1
UCEC	S6_pS240_S244 →	+0.452	+3.000	.010	.036	3	1
UCEC	TIGAR →	+0.140	+1.611	.036	.043	3	1
UCEC	ASNS →	+0.476	+2.321	.002	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Caspase-7-cleavedD198 by IL20RA expression — UCEC

Explore this box plot interactively →