IL20RA

Across TCGA cell cohorts, IL20RA mutation is significantly associated with the RNA expression of many other genes, with 169 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL20RA-associated genes across cancer lineages are SPRR2B, DUOXA2, and TCF23. Each is linked with IL20RA in more than 1 cancer types. Because this analysis shows association rather than direction, both IL20RA-to-partner and partner-to-IL20RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPRR2B grouped by IL20RA-low versus IL20RA-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL20RA→partner) and Y-score (partner→IL20RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SPRR2B →	+0.076	+4.569	<.001	.003	3	2
SKIN	DUOXA2 →	+0.147	+4.029	<.001	.004	3	1
SKIN	TCF23 →	+0.005	+4.217	<.001	.001	3	1
SKIN	ACER1 →	+0.025	+4.562	<.001	<.001	3	1
SKIN	KRT24 →	+0.260	+3.684	<.001	.006	3	1
SKIN	WFDC12 →	+0.076	+3.920	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 169 associations by consensus.

SPRR2B by IL20RA expression — BLOOD_Leukemia

Explore this box plot interactively →