IL20

Across TCGA patient cohorts, IL20 mutation is significantly associated with the RNA expression of many other genes, with 121 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL20-associated genes across cancer lineages are RN7SL750P, OR5M13P, and SNORD116-11. Each is linked with IL20 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL20-to-partner and partner-to-IL20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL750P grouped by IL20-low versus IL20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL20→partner) and Y-score (partner→IL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL750P →	+0.188	+2.335	.004	.004	3	2
SKCM	OR5M13P →	+0.057	+3.990	<.001	.009	3	2
SKCM	SNORD116-11 →	+0.160	+4.411	<.001	.005	3	2
CESC	RN7SL813P →	+0.195	+5.103	<.001	.008	3	1
CESC	MTCO2P4 →	+0.180	+5.418	<.001	.005	3	1
CESC	OR4C1P →	+0.075	+6.837	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 121 associations by consensus.

RN7SL750P by IL20 expression — UCEC

Explore this box plot interactively →