IL20

Across TCGA patient cohorts, IL20 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL20-associated genes across cancer lineages are FASN, Myosin-IIa_pS1943, and PKC-delta_pS664. Each is linked with IL20 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL20-to-partner and partner-to-IL20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by IL20-low versus IL20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL20→partner) and Y-score (partner→IL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.419	+3.321	.042	.010	3	1
UCEC	Myosin-IIa_pS1943 →	+0.224	+2.183	.038	.035	3	1
UCEC	PKC-delta_pS664 →	-0.162	-2.999	.010	.035	3	1
UCEC	VHL →	-0.816	-3.000	.021	.036	3	1
UCEC	c-Met_pY1235 →	+0.081	+3.321	.037	.010	3	1
UCEC	Caspase-7-cleavedD198 →	+0.635	+2.827	.041	.035	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

FASN by IL20 expression — UCEC

Explore this box plot interactively →