IL20

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IL20 RNA expression is significantly associated with the go_rna of many other GO terms, with 499 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible IL20-associated GO terms across cancer lineages are Cellular response to ether, Metanephric proximal tubule development, and Regulation of prostaglandin secretion. Each is linked with IL20 in more than 4 cancer types. Because this analysis shows association rather than direction, both IL20-to-partner and partner-to-IL20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to ether grouped by IL20-low versus IL20-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL20→partner) and Y-score (partner→IL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTCellular response to ether →+0.138+0.402<.001.00235
SKINMetanephric proximal tubule development →-0.113-0.091.003.00434
UPPER_AERODIGESTIVE_TRACTRegulation of prostaglandin secretion →+0.164+0.453.001.00133
UPPER_AERODIGESTIVE_TRACTReceptor diffusion trapping →-1.522-0.460<.001.00233
UPPER_AERODIGESTIVE_TRACTPostsynaptic neurotransmitter receptor diffusion trapping →-1.522-0.460<.001.00233
UPPER_AERODIGESTIVE_TRACTNeurotransmitter receptor diffusion trapping →-1.522-0.460<.001.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 499 associations by consensus.

Cellular response to ether by IL20 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Cellular response to ether in IL20-low vs IL20-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration