IL1RL2

Across TCGA patient cohorts, IL1RL2 mutation is significantly associated with the RNA expression of many other genes, with 1,839 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL1RL2-associated genes across cancer lineages are RNU2-36P, MIR8075, and RNU6-202P. Each is linked with IL1RL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both IL1RL2-to-partner and partner-to-IL1RL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-36P grouped by IL1RL2-low versus IL1RL2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1RL2→partner) and Y-score (partner→IL1RL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU2-36P →	+1.053	+4.187	<.001	.001	3	3
BRCA	MIR8075 →	+0.285	+4.857	<.001	.004	3	2
CESC	RNU6-202P →	+0.435	+5.539	<.001	.004	3	2
CESC	MIR4674 →	+0.577	+5.103	<.001	.008	3	2
LGG	MTND3P16 →	+0.209	+5.846	<.001	.003	3	2
SARC	IGHD4-4 →	+1.451	+5.778	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,839 associations by consensus.

RNU2-36P by IL1RL2 expression — COAD

Explore this box plot interactively →