IL1RAPL1

Across TCGA patient cohorts, IL1RAPL1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,194 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL1RAPL1-associated genes across cancer lineages are UPB1, POLR2F, and SOX10. Each is linked with IL1RAPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL1RAPL1-to-partner and partner-to-IL1RAPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL1RAPL1 versus UPB1 in GBM, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1RAPL1→partner) and Y-score (partner→IL1RAPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	UPB1 →	+0.133	+0.380	.005	.003	3	1
GBM	POLR2F →	+0.502	+0.553	.001	<.001	3	1
GBM	SOX10 →	+1.700	+0.559	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.281	+0.599	<.001	<.001	3	1
GBM	TPTEP1 →	+0.870	+0.378	.009	.003	3	1
GBM	RAB36 →	-0.666	-0.372	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,194 associations by consensus.

IL1RAPL1 vs UPB1 — GBM

Explore this scatter interactively →