IL1RAPL1

Across TCGA cell cohorts, IL1RAPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,893 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible IL1RAPL1-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Nucleotide-sugar metabolic process, and Regulation of plasminogen activation. Each is linked with IL1RAPL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both IL1RAPL1-to-partner and partner-to-IL1RAPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by IL1RAPL1-low versus IL1RAPL1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1RAPL1→partner) and Y-score (partner→IL1RAPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of focal adhesion assembly →	+0.165	+0.532	.001	.003	2	8
SKIN	Nucleotide-sugar metabolic process →	+0.049	+1.473	<.001	<.001	3	7
CNS	Regulation of plasminogen activation →	+0.223	+0.968	<.001	.001	3	7
SKIN	Regulation of protein exit from endoplasmic reticulum →	+0.067	+1.602	.009	<.001	3	7
SOFT_TISSUE	Protein stabilization →	+0.037	+0.809	<.001	.004	3	6
SKIN	Morphogenesis of an epithelial fold →	-0.995	-1.489	.002	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,893 associations by consensus.

Positive regulation of focal adhesion assembly by IL1RAPL1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →