IL1R1

Across TCGA patient cohorts, IL1R1 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,256 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL1R1-associated proteins across cancer lineages are C1S, NNMT, and RFC1. Each is linked with IL1R1 in more than 7 cancer types. Because this analysis shows association rather than direction, both IL1R1-to-partner and partner-to-IL1R1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL1R1 versus C1S in COAD, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1R1→partner) and Y-score (partner→IL1R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C1S →	+0.586	+0.951	<.001	<.001	3	8
GBM	NNMT →	+1.383	+1.561	<.001	<.001	3	8
OV	RFC1 →	-0.269	-0.729	.001	.003	3	7
GBM	LUC7L3 →	-0.320	-1.361	<.001	<.001	3	7
OV	NCL →	-0.438	-0.796	<.001	.001	3	7
GBM	SERPING1 →	+0.561	+1.292	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,256 associations by consensus.

IL1R1 vs C1S — COAD

Explore this scatter interactively →