IL19

Across TCGA patient cohorts, IL19 mutation is significantly associated with the RNA expression of many other genes, with 98 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL19-associated genes across cancer lineages are VN1R105P, RNU6-711P, and KNOP1P4. Each is linked with IL19 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL19-to-partner and partner-to-IL19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R105P grouped by IL19-low versus IL19-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL19→partner) and Y-score (partner→IL19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VN1R105P →	+0.054	+5.124	<.001	.008	3	2
HNSC	RNU6-711P →	+0.389	+5.303	<.001	.006	3	2
UCEC	KNOP1P4 →	+0.168	+3.903	<.001	.004	3	2
BRCA	RNA5SP414 →	+0.216	+8.471	<.001	.005	3	1
HNSC	RNU6-1222P →	+0.392	+5.655	<.001	.004	3	1
HNSC	RNU6-603P →	+0.425	+5.505	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 98 associations by consensus.

VN1R105P by IL19 expression — HNSC

Explore this box plot interactively →