IL18BP

Across TCGA patient cohorts, IL18BP protein abundance is significantly associated with the RNA expression of many other genes, with 5,161 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL18BP-associated genes across cancer lineages are MARCHF1, MAN1C1, and SLC46A3. Each is linked with IL18BP in more than 4 cancer types. Because this analysis shows association rather than direction, both IL18BP-to-partner and partner-to-IL18BP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL18BP versus MARCHF1 in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL18BP→partner) and Y-score (partner→IL18BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MARCHF1 →	+0.559	+1.166	.002	.001	3	5
BRCA	MAN1C1 →	+0.982	+0.931	<.001	.003	3	4
BRCA	SLC46A3 →	+1.126	+1.047	<.001	<.001	3	4
HNSC	SAMD3 →	+1.253	+1.183	<.001	<.001	3	4
CCRCC	CR1 →	+0.852	+0.847	.001	.002	3	4
BRCA	ACAP1 →	+0.980	+0.947	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,161 associations by consensus.

IL18BP vs MARCHF1 — BRCA

Explore this scatter interactively →