IL18BP

Across TCGA cell cohorts, IL18BP RNA expression is significantly associated with the RNA expression of many other genes, with 10,412 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL18BP-associated genes across cancer lineages are RNF121, LY6G5B, and FNBP4. Each is linked with IL18BP in more than 18 cancer types. Because this analysis shows association rather than direction, both IL18BP-to-partner and partner-to-IL18BP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL18BP versus RNF121 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL18BP→partner) and Y-score (partner→IL18BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RNF121 →	+1.264	+1.339	<.001	<.001	3	19
LIVER	LY6G5B →	+1.809	+2.099	.001	<.001	3	17
OVARY	FNBP4 →	+1.069	+1.098	<.001	<.001	3	17
LARGE_INTESTINE	DMTF1 →	+1.214	+1.515	<.001	<.001	3	16
LARGE_INTESTINE	TSSK4 →	+1.294	+1.277	<.001	<.001	3	16
BONE	TMEM259 →	+1.085	+1.380	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,412 associations by consensus.

IL18BP vs RNF121 — UPPER_AERODIGESTIVE_TRACT

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