IL17RB

Across TCGA pan-cancer cohorts, IL17RB Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IL17RB data layer compared with 27 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IL17RB Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated IL17RB expression acts as an unfavorable survival marker.

HNSC, LUAD, and UCEC are the cancer types where IL17RB Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.176	0.685	.024	30	view →
LUAD	DFS	Median	IV	0.342	0.893	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

IL17RB–HNSC (OS)

Open the HNSC breakdown →