IL17F

Across TCGA patient cohorts, IL17F protein abundance is significantly associated with the RNA expression of many other genes, with 439 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IL17F-associated genes across cancer lineages are KCTD17, PROCR, and TPD52L1. Each is linked with IL17F in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17F-to-partner and partner-to-IL17F results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL17F versus KCTD17 in UCEC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17F→partner) and Y-score (partner→IL17F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KCTD17 →	+0.912	+0.995	.004	.009	3	1
UCEC	PROCR →	+1.000	+1.219	.005	.002	3	1
UCEC	TPD52L1 →	+1.232	+1.212	<.001	.002	3	1
UCEC	TXNDC15 →	+0.865	+0.867	.002	.009	3	1
UCEC	DCN →	+2.436	+1.219	.008	<.001	3	1
UCEC	PLCH1 →	+1.474	+1.011	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 439 associations by consensus.

IL17F vs KCTD17 — UCEC

Explore this scatter interactively →