IL17F

Across TCGA cell cohorts, IL17F RNA expression is significantly associated with the go_rna of many other GO terms, with 498 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IL17F-associated GO terms across cancer lineages are Positive regulation of growth, Icosanoid transport, and Adenylate cyclase-activating dopamine receptor signaling pathway. Each is linked with IL17F in more than 2 cancer types. Because this analysis shows association rather than direction, both IL17F-to-partner and partner-to-IL17F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of growth grouped by IL17F-low versus IL17F-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17F→partner) and Y-score (partner→IL17F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of growth →	-0.024	-0.019	.005	.006	3	3
BLOOD_Leukemia	Icosanoid transport →	-0.058	-0.019	.002	.003	3	3
BLOOD_Leukemia	Adenylate cyclase-activating dopamine receptor signaling pathway →	+0.139	+0.019	<.001	.002	3	3
LUNG_NSCLC_LUAD	Calcium ion transport →	-0.045	-0.025	<.001	.004	3	3
BONE	Regulation of heterochromatin formation →	+0.112	+0.128	<.001	.004	3	3
LUNG_NSCLC_LUAD	Protein desumoylation →	+0.048	+0.020	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 498 associations by consensus.

Positive regulation of growth by IL17F expression — BLOOD_Leukemia

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