IL17A

Across TCGA patient cohorts, IL17A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,829 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible IL17A-associated GO terms across cancer lineages are Immunoglobulin production, B cell mediated immunity, and Response to chemokine. Each is linked with IL17A in more than 15 cancer types. Because this analysis shows association rather than direction, both IL17A-to-partner and partner-to-IL17A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin production grouped by IL17A-low versus IL17A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17A→partner) and Y-score (partner→IL17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Immunoglobulin production →	+0.064	+0.340	<.001	<.001	3	16
STAD	B cell mediated immunity →	+0.057	+0.300	<.001	.001	3	13
STAD	Response to chemokine →	+0.040	+0.312	<.001	<.001	3	13
BRCA	Positive regulation of T cell proliferation →	+0.041	+0.029	<.001	<.001	3	13
BRCA	Alpha-beta T cell activation →	+0.037	+0.030	<.001	<.001	3	12
BRCA	Negative regulation of lymphocyte activation →	+0.037	+0.030	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,829 associations by consensus.

Immunoglobulin production by IL17A expression — STAD

Explore this box plot interactively →