IL17A

Across TCGA cell cohorts, IL17A RNA expression is significantly associated with the RNA expression of many other genes, with 351 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IL17A-associated genes across cancer lineages are TGM6, SERPINA9, and ZPBP2. Each is linked with IL17A in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17A-to-partner and partner-to-IL17A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL17A versus TGM6 in STOMACH, with a Pearson correlation of 0.99.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17A→partner) and Y-score (partner→IL17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	TGM6 →	+1.080	+0.021	<.001	.006	3	2
PANCREAS	SERPINA9 →	+0.082	+0.002	.007	.002	3	2
BLOOD_Leukemia	ZPBP2 →	+0.520	+0.001	.002	<.001	3	2
BREAST	RTP5 →	+0.045	+0.024	<.001	.005	3	2
STOMACH	OR6M1 →	+0.078	+0.054	<.001	<.001	3	2
STOMACH	DEFA3 →	+0.683	+0.036	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 351 associations by consensus.

IL17A vs TGM6 — STOMACH

Explore this scatter interactively →