IL17A

Across TCGA cell cohorts, IL17A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible IL17A-associated genes across cancer lineages are LGALS14. Each is linked with IL17A in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17A-to-partner and partner-to-IL17A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGALS14 grouped by IL17A-low versus IL17A-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17A→partner) and Y-score (partner→IL17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	LGALS14 →	+0.032	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

LGALS14 by IL17A expression — SKIN

Explore this box plot interactively →