IL15

Across TCGA cell cohorts, IL15 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,234 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IL15-associated GO terms across cancer lineages are Cytolysis in another organism, Antigen processing and presentation of peptide antigen via MHC class I, and Regulation of plasminogen activation. Each is linked with IL15 in more than 13 cancer types. Because this analysis shows association rather than direction, both IL15-to-partner and partner-to-IL15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytolysis in another organism grouped by IL15-low versus IL15-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL15→partner) and Y-score (partner→IL15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Cytolysis in another organism →	+1.709	+2.112	.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Antigen processing and presentation of peptide antigen via MHC class I →	+0.187	+1.032	.001	.002	3	14
BONE	Regulation of plasminogen activation →	+0.315	+1.861	<.001	<.001	3	13
URINARY_TRACT	CD8-positive, alpha-beta T cell homeostasis →	+0.123	+1.357	<.001	<.001	3	12
OVARY	Regulation of leukocyte differentiation →	+0.054	+1.192	.001	.004	3	12
BREAST	Negative regulation of response to biotic stimulus →	+0.095	+1.309	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,234 associations by consensus.

Cytolysis in another organism by IL15 expression — LIVER

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