IL13RA2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IL13RA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,829 significant associations in total. CNS shows the largest number of these associations.

The most reproducible IL13RA2-associated GO terms across cancer lineages are Positive regulation of cell-substrate junction organization, Protein localization to endosome, and Positive regulation of focal adhesion assembly. Each is linked with IL13RA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both IL13RA2-to-partner and partner-to-IL13RA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell-substrate junction organization grouped by IL13RA2-low versus IL13RA2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL13RA2→partner) and Y-score (partner→IL13RA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEPositive regulation of cell-substrate junction organization →+0.118+2.928<.001<.00138
BONEProtein localization to endosome →+0.215+2.021<.001.00837
BONEPositive regulation of focal adhesion assembly →+0.217+1.205<.001.00328
OESOPHAGUSRegulation of focal adhesion assembly →+0.079+0.365.003.00737
OESOPHAGUSRegulation of cell-substrate junction assembly →+0.079+0.365.003.00737
SOFT_TISSUERegulation of cell-substrate junction organization →+0.063+2.034.005.00336
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,829 associations by consensus.

Positive regulation of cell-substrate junction organization by IL13RA2 expression — SOFT_TISSUE

Box plot of Positive regulation of cell-substrate junction organization in IL13RA2-low vs IL13RA2-high samples in SOFT_TISSUE.

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Exploration