IL13

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, IL13 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated IL13 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IL13 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated IL13 expression acts as an unfavorable survival marker.

HNSC are the cancer types where IL13 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSMedianII,III,IV0.1870.756.00124view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

IL13–HNSC (OS)

Kaplan–Meier survival curve for IL13 mutant vs wild-type samples in HNSC.

Open the HNSC breakdown →

Exploration