IL13

Across TCGA patient cohorts, IL13 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL13-associated genes across cancer lineages are RPS15AP3, MIR5585, and DNAJB8-AS1. Each is linked with IL13 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL13-to-partner and partner-to-IL13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS15AP3 grouped by IL13-low versus IL13-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL13→partner) and Y-score (partner→IL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPS15AP3 →	+0.307	+6.003	<.001	.002	3	2
SKCM	MIR5585 →	+0.637	+3.683	<.001	.003	3	2
UCEC	DNAJB8-AS1 →	+0.031	+3.198	.006	.007	3	2
UCEC	RNVU1-26 →	+0.319	+2.670	.002	.009	3	1
COAD	OR9Q2 →	+0.091	+6.721	<.001	<.001	3	1
COAD	MIR572 →	+0.719	+6.917	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

RPS15AP3 by IL13 expression — COAD

Explore this box plot interactively →