IL13

Across TCGA patient cohorts, IL13 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL13-associated genes across cancer lineages are Tuberin and STAT3_pY705. Each is linked with IL13 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL13-to-partner and partner-to-IL13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin grouped by IL13-low versus IL13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL13→partner) and Y-score (partner→IL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Tuberin →	+0.347	+3.000	.026	.037	2	1
UCEC	STAT3_pY705 →	-0.593	-3.000	<.001	.037	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Tuberin by IL13 expression — UCEC

Explore this box plot interactively →