IL12B

Across TCGA patient cohorts, IL12B protein abundance is significantly associated with the RNA expression of many other genes, with 2,731 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL12B-associated genes across cancer lineages are MYZAP, MAPK10, and UST. Each is linked with IL12B in more than 1 cancer types. Because this analysis shows association rather than direction, both IL12B-to-partner and partner-to-IL12B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL12B versus MYZAP in LUAD, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL12B→partner) and Y-score (partner→IL12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MYZAP →	+0.901	+1.219	.004	.001	3	2
UCEC	MAPK10 →	+0.662	+0.732	.003	.001	3	2
GBM	UST →	+0.855	+0.696	.001	<.001	3	2
UCEC	SOCS2 →	+0.632	+0.770	.003	<.001	3	2
UCEC	FOXP2 →	+0.953	+0.939	<.001	.001	3	2
GBM	PPFIA2 →	+1.281	+0.812	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,731 associations by consensus.

IL12B vs MYZAP — LUAD

Explore this scatter interactively →