IL12B

Across TCGA cell cohorts, IL12B mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL12B-associated genes across cancer lineages are CD300H. Each is linked with IL12B in more than 1 cancer types. Because this analysis shows association rather than direction, both IL12B-to-partner and partner-to-IL12B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by IL12B-low versus IL12B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL12B→partner) and Y-score (partner→IL12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD300H by IL12B expression — LARGE_INTESTINE

Explore this box plot interactively →