IL12A

Across TCGA patient cohorts, IL12A RNA expression is significantly associated with the RNA expression of many other genes, with 16,415 significant associations in total. UVM shows the largest number of these associations.

The most reproducible IL12A-associated genes across cancer lineages are CCNL1, PARP14, and IL12A-AS1. Each is linked with IL12A in more than 25 cancer types. Because this analysis shows association rather than direction, both IL12A-to-partner and partner-to-IL12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL12A versus CCNL1 in UVM, with a Pearson correlation of 0.49.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL12A→partner) and Y-score (partner→IL12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	CCNL1 →	+1.278	+0.110	<.001	<.001	3	26
UVM	PARP14 →	+1.297	+0.105	<.001	<.001	3	25
LAML	IL12A-AS1 →	+2.279	+1.184	<.001	<.001	3	25
UVM	FNBP4 →	+1.222	+0.085	<.001	<.001	3	25
SCLC	CIITA →	+1.332	+0.683	.001	.003	1	26
ESCA	IRF1-AS1 →	+0.665	+0.541	<.001	<.001	2	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,415 associations by consensus.

IL12A vs CCNL1 — UVM

Explore this scatter interactively →